The research paper was done in 2020 by Harvard University and other institutions. It showed how NAD+ was able to rescue fertility in old mice and their pups were also able to reproduce.
This research discusses NAD+ activation and cellular processes associated with Sirtuins that effect both male and female infertility.
This research was conducted in Japan and show how SIRT3, a NAD+ dependent gene is critical for fertilization and blastocyst development.
This research discuss how mitochondrial dysfunction is associated with neurodegeneration and Parkinson’s disease. It also discuss strategies to mitigate using NAD+ pathways for neural regeneration.
This research shows clear evidence in mice of NAD+ effects on offspring development, brain development and benefits to mothers that supplemented.
The above research paper for Harvard and David Sinclair outlines how NAD+ is used for Metaboic and cardiovascular disease.
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