The research paper was done in 2020 by Harvard University and other institutions. It showed how NAD+ was able to rescue fertility in old mice and their pups were also able to reproduce.
Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility
Regenerative Medicine
August 25, 2020
This research discusses NAD+ activation and cellular processes associated with Sirtuins that effect both male and female infertility.
