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This research was conducted in Japan and show how SIRT3, a NAD+ dependent gene is critical for fertilization and blastocyst development.
Regen Med Asia / NAD+ / Sirt3 protects in vitro–fertilized mouse preimplantation embryos against oxidative stress–induced p53-mediated developmental arrest
This research was conducted in Japan and show how SIRT3, a NAD+ dependent gene is critical for fertilization and blastocyst development.
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The research paper was done in 2020 by Harvard University and other institutions. It showed how NAD+ was able to rescue fertility in old mice and their pups were also able to reproduce.
This research discusses NAD+ activation and cellular processes associated with Sirtuins that effect both male and female infertility.
This research discuss how mitochondrial dysfunction is associated with neurodegeneration and Parkinson’s disease. It also discuss strategies to mitigate using NAD+ pathways for neural regeneration.
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