The above below discusses how NAD+ declines as we age, and by 40 we have lost 50% of our NAD+.
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The research paper was done in 2020 by Harvard University and other institutions. It showed how NAD+ was able to rescue fertility in old mice and their pups were also able to reproduce.
This research discusses NAD+ activation and cellular processes associated with Sirtuins that effect both male and female infertility.
This research was conducted in Japan and show how SIRT3, a NAD+ dependent gene is critical for fertilization and blastocyst development.
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NAD+ Repletion Rescues Female Fertility during Reproductive Aging
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